A case-based discussion of ethical issues arising from the
increasing use of computers in medicine, psychology, and
pharmacy. Presents 130 case studies emerging from a case-collection
project of the American Medical Informatics Association.
A comprehensive discussion by many noted authorities of all
aspects of IRB organization and review. A good beginning point
for any issue concerning the IRB.
An overview of the issues treated in greater depth in the work
listed above.
Ethical Issues in Drug Testing, Approval and Pricing: The Clot
Dissolving Drugs
Baruch A. Brody
Oxford University Press, New York, 1995
Uses the example of the development of thrombolytic
drugs to explore gaps in regulations governing the testing,
approval, and marketing of new drugs in general. Discusses
placebo controls, consent for emergency research, balancing efficacy
and safety, and avoiding conflict of interest in clinical
trials.
The Ethics of Biomedical Research: An International Perspective
Baruch A. Brody
Oxford University Press, New York, 1998
A discussion of general issues in research
with both animals and humans, together with chapters on more
specific topics such as genetic research, reproductive and fetal
research, and international research ethics policies.
Ethical Issues in Research
Darwin Cheney
University Publishing Group, Inc., Frederick, MD, 1993
A collection of essays on the responsible conduct
of research. Part I covers misrepresentation of data and Part II
deals with conflict of interest. Especially good articles on
authorship.
Belmont Revisited: Ethical Principles for Research with Human
Subjects
James F. Childress, Eric M. Meslin and Harold T. Shapiro
Georgetown University Press, Washington, DC, 2005
An excellent discussion by noted scholars of the
history and philosophical issues underlying the Belmont
Report, the foundational document of research ethics in the U.S.
A clear and comprehensive debate about the moral
status of animals, including their use in medical research, by
two leading figures on the topic.
Ethics in Mental Health Research
James M. DuBois
Oxford University Press, New York, 2007
A discussion of central issues in research ethics – informed
consent, balancing harms and benefits, protecting privacy and
confidentiality, justice in recruiting research participants – with
a focus on mental health research. Includes several cases on
conflict of interest.
University Presses of New England, Hanover, NH, 1997.
A good collection of essays on many aspects of
scientific misconduct, especially falsification of data,
conflict of interest, and institutional responsibility.
Ethical and Regulatory Aspects of Clinical Research: Readings and
Commentary
Ezekiel J. Emanuel, Robert A. Crouch, John D. Arras, Jonathan D.
Moreno and Christine Grady
The Johns Hopkins University Press, Baltimore, 2003
A very large collection of readings by leading
figures on numerous topics, including clinical trial design,
participant recruitment, informed consent, special populations,
genetic research, and scientific misconduct.
Another large collection of readings on the topics
listed immediately above
.
The Search for an AIDS Vaccine: Ethical Issues in the Development
and Testing of a Preventive HIV Vaccine
Christine Grady
Indiana University Press, Bloomington, 1995
An exploration of ethical issues in vaccine
research, which differs in significant ways from drug research,
and the special challenges facing development of a vaccine for HIV.
Ethical and Legal Issues in AIDS Research
Joni N. Gray, Phillip M. Lyons, Jr. and Gary B. Melton
The Johns Hopkins University Press, Baltimore, 1995
Discusses ethical and legal problems in
psychosocial research on AIDS, which, due to the possibility of
discrimination, requires special attention to preserving
confidentiality, legal protection of participants, informed consent,
and the balance between individual privacy and public health.
Issues in Conducting Research With and About Older Persons – Ethics,
Law and Aging Review: Volume 8
Marshall B. Kapp
Springer Publishing Company, New York, 2002
Special edition of the journal focused on research
in geriatric populations, especially issues of decisional
capacity.
Breakout: The Evolving Threat of Drug-Resistant Disease
Marc Lappe
Sierra Club Books, San Francisco, 1995
Discusses the potential threat of emerging viruses
and drug-resistant bacteria, and suggests public health
strategies for countering them based on an evolutionary approach
to disease.
Ethics and Regulation of Clinical Research 2nd Ed
Robert Levine
Yale University Press, New Haven, 1988
A classic text and reference in research ethics,
covering all major issues, by a respected researcher, IRB
chairman, and journal editor.
An excellent primer that clarifies all aspects of an
IRB’s work, including definitions of key terms, understanding
of the scientific protocol, assessment of risk, and elements of
informed consent.
Minnesota Journal of Law, Science, and Technology
Volume
6, Issue 1, December 2004
Includes essays on open source biotechnology
movement and intellectual property rights for the public
good
Trust and Integrity in Biomedical Research
Thomas Murray Josephine Johnson, editors
The Johns
Hopkins Press, Baltimore, 2010
A collection of essays on various aspects of
financial conflict of interest.
Ethical
and Policy Issues in Research Involving Human Participants:
Volume
1: Reports and Recommendations
National
Bioethics Advisory Commission, 2001
National
Symposium on Imperatives in Research Animal Use: Scientific Needs
and Animal Welfare
National
Institutes of Health, Office for Protection from Research Risks,
Bethesda, MD 1984.
Proceedings of an early symposium on the use of
animals in research. Most contributions are dated, while a few
retain some currency.
Research
Ethics: Cases & Materials
Robin Levin Penslar
Indiana
University Press, Bloomington, 1995
Contains both essays and cases for teaching research
ethics; focused not on clinical research, but on basic science,
psychology, and history. Includes an excellent annotated
bibliography in these areas.
Beyond
Prejudice: The Moral Significance of Human and Nonhuman Animals
Evelyn B. Pluhar
Duke
University Press, Durham, 1995
A
careful and thorough defense of the moral status of animals,
developing the view that any animal capable of feeling and caring
what happens to itself has some rights that should be respected.
Animal
Sacrifices: Religious Perspectives on the Use of Animals in Science
Tom Regan
Temple
University Press, Philadelphia, 1986
A collection of essays examining the animal-rights
debate from the point of view of religion.
Children
in Medical Research
Lainie Friedman Ross
Oxford
University Press, New York, 2006
A critical evaluation of the special protections
afforded children under current federal regulations, describing
the shift from the earlier focus on protection to the current
concern about access to research, and making policy recommendations.
Morals,
Reason, and Animals
S. F. Sapontzis
Temple
University Press, Philadelphia, 1987
A philosophical defense of the view that animals have
rights, including a chapter on the use of animals in research.
Responsible Conduct of Research
Adil E.
Shamoo and David B. Resnik
Oxford
University Press, New York, 2009
A comprehensive discussion of topics in the ethical
conduct of scientific research, including, but not limited
to, research misconduct.
Medical
Innovations and Bad Outcomes: Legal, Social and Ethical Responses
Mark Siegler, Stephen Toulmin, Franklin E. Zimring, and
Kenneth F. Schaffner
Health
Administration Press, Ann Arbor, 1987
A collection of essays on dealing with bad
outcomes of innovation and research, - how we attribute
responsibility and provide compensation to the injured.
The
Stored Tissue Issue: Biomedical Research Ethics, and Law in the Era
ofGenomic Medicine
Robert F. Weir, Robert S. Olick and Jeffrey C. Murray
Oxford
University Press, New York, 2004
Issues raised by the banking of human tissues,
DNA, and genetic data, especially ownership, consent, privacy,
and trust.
The
Ethics of Research Involving Human Subjects: Facing the 21st
Century
Harold Y. Vanderpool
University Publishing Group, Inc., Frederic, MD, 1996
Essays by leading thinkers on the ethical principles
underlying research with humans, conflicts of interest,
cross-cultural research, and other issues.
The Use
of Human Fetal Tissue: Scientific, Ethical and Policy Concerns
Dorothy E. Vawter, Warren Kearney, Karen G. Gervais,
Arthur L. Caplan
Daniel Garry and Carol Tauer
University of Minnesota, Minneapolis, 1990
An early policy statement on the use of human fetal
tissue in both clinical medicine and research.
The
Ethics of Pediatric Research
David S. Wendler
Oxford
University Press, New York, 2010
A thorough scholarly treatment of the problem of
non-beneficial pediatric research, that is, research that
exposes some children to risk solely for the benefit of unrelated
others
The
Abuse of Man
Wolfgang
Meyers
Ardor
Scribindi, Ltd., New York, 2003
Subtitled “An illustrated history of dubious medical
experimentation,” the book provides 600 pages of documentation of
unethical research
