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John C. Marecki, Ph.D. Phone: 501.364.2706 |
Education:
Ph.D. University of Colorado Health Sciences Center, Biochemistry, 2002
B.S. University of Denver, Biochemistry, 1995
Research Interests:
Dr. Marecki has an interest in exploring the contribution of dietary factors as well as excessive energy intake to the development of childhood obesity, and determining the underlying molecular mechanisms of associated complications including fatty liver disease, insulin resistance, inflammation and steatohepatitis. Through the use of carefully developed animal models, Dr. Marecki aims to obtain a better understanding of the metabolic basis for the development and progression of childhood obesity and produce innovative tools for prevention and treatment.
Selected Publications | Publications on Pub Med
He L., J.C. Marecki, G. Serrero, F.A. Simmen, M.J. Ronis, T.M. Badger. 2007 Dose dependent effects of alcohol on insulin signaling: Partial explanation for biphasic alcohol impact on human health. Mol. Endocrinol. 21(10):2541-2550.
Marecki, J.C., C.D. Cool, J.E. Parr, V.E. Beckey, P.A. Luciw, A.F. Tarantal, A. Carville, R.P. Shannon, A. Cota-Gomez, R.M. Tuder, N.F. Voelkel and S.C. Flores. 2006. HIV-1 Nef is associated with angioproliferative pulmonary arterial disease in SHIVnef-infected macaques. Am. J. Crit. Care Med. 174(4):437-45.
Marecki, J., C. Cool, N. Voelkel, P. Luciw and S. Flores. 2005. Evidence for vascular remodeling in the lungs of macaques infected with simian immunodeficiency virus/HIV Nef recombinant virus. Chest 128:621S-622S.
Ling, X., A. Cota-Gomez, N.C. Flores, D. Hernandez-Saavedra, J.M. McCord, J.C. Marecki, K. Haskins, M. McDuffie, K. Powers, J. Kench, M. Oka, I. McMurtry and S.C. Flores. 2005. Alterations in redox homeostasis and prostaglandins impair endothelial-dependent vasodilation in euglycemic autoimmune nonobese diabetic mice. Free Radic. Biol. Med. 39:1089-1098.
Marecki, J.C. and J.M. McCord. 2002. The inhibition of poly(ADP-ribose) polymerase enhances growth rates of ataxia telangiectasia cells. Arch. Biochem. Biophys. 402:227-234.
